If you have ever had fever and was afraid it was too much, you may have another reason to just allow the course of life to take effect. But there is a limit it must not exceed. 

There is a study that now explains why some persons may not take medications and still recover from fever. 

Researchers from the Shanghai Institute of Biochemistry and Cell Biology of Chinese Academy of Sciences on Tuesday suggested that patients with a fever higher than 38.5 degrees Celsius should take fever-reducing medicines after sustaining for about six hours. 

A fever is a higher-than-normal body temperature and is a part of our body’s natural response to infection.

The average normal body temperature is 98.6 degrees Fahrenheit (37 degrees Celsius), when the body’s temperature rises a few degrees above normal, it is a sign that the body is fighting infection and is generally not cause for concern. 

However, a fever that goes above 102 degrees Fahrenheit (39.2 degree Celsius) is a cause for concern, and treatment should be initiated.

The researchers explained that the fever could promote the protection mechanism of the human body in fighting against pathogen infection. 

"The protein Hsp90 contained in the immune cells can be motivated when the body’s temperature goes up to 38.5 degrees Celsius. 

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“The protein will then be bonded on the cell membrane. 

“It will now work with integrins alpha4 to accelerate the trafficking of the immune cells to the infection site in order to get rid of the pathogen,’’ the study published in the journal Immunity said 

Working with mice with fevers induced by salmonella infections, the researchers found the artificial destruction of the combination of Hsp90 and alpha4 will greatly increase the death rate during bacterial infection, Xinhua reports. 

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