Germany will be facing Brazil in an international friendly on Tuesday with a depleted squad.

Thomas Mueller along with midfielders Mesut Ozil and Emre Can have all been ruled out of the game billed to take place in Berlin according to a statement from the German Football Association (DFB).

The 28-year-old Mueller and Arsenal playmaker Ozil both featured in Germany’s high tempo 1-1 friendly draw with Spain on Friday.

The Bayern Munich forward scored the equaliser to cancel out Rodrigo Moreno’s early opener.

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“Thomas Mueller and Mesut Ozil will not travel with the squad to Berlin,” the DFB said on their official Twitter account.

Can, 24, was ruled out of the Spain match with a back injury and has returned to Premier League side Liverpool after failing to recover in time for the Brazil clash.

“With ongoing back problems leaving him without a chance of playing against Brazil on Tuesday, Emre Can has returned home today. Get well soon!,” DFB tweeted on Saturday.

The national team’s governing body also said that Bayern Munich midfielder Sebastian Rudy, who missed the Spain game following the birth of his son on Thursday, had rejoined the squad.

Holders Germany have been drawn in Group F at the World Cup in June, along with Mexico, South Korea and Sweden.